Why You Should Take Systemic Enzymes

Written by Jason FerruggiaTopics: Nutrition

Today I have a guest post from Dr. William Wong about one of my favorite, secret supplements for fighting inflammation; systemic enzymes. You never really hear about these which is a shame because they’re awesome for anyone over 35 or those guys who are beat up from years of athletics, heavy training, etc.


What have the years of pounding your knees, grinding your shoulders and pushing all of the other joints of your body done to that smooth sponge like gliding surface?

The hyaline was formed early in life from something called mucopolysaccharides. Your body stopped making the stuff somewhere during or after puberty. Now, the inside of the joint has no blood supply. The articulating surfaces are fed directly by the mucous synovial fluid which gets it’s supply of nutrients through the joint capsule membrane from the blood supply on it’s outside. If we still made these mucopolysaccharides our joints hardly ever wear. But we don’t so they do.

Dr.Max Wolf M.D. and Ph.D. times 7 of Columbia University is widely acknowledged as the father of systemic oral enzyme therapy. (1). Wolf found that as we age or are under stress our bodies own production of enzymes is depleted. Age related changes he said are directly attributable to depletion of enzymes. Systemic enzymes differ from digestive enzymes in that the tablets are taken in between meals so that the constituents can be absorbed into the blood stream and do their work there instead of expending their action on digesting food.

With 40 years of use and over 160 peer reviewed verifying studies behind it, systemic enzymes are the second best selling over the counter preparation in Germany. When a joint or any soft tissue is injured or infirm the body creates irritants called Circulating Immune Complexes. It’s these complexes that cause the inflammation of joint capsules, bursae, tendons, muscles, blood vessels, internal organs etc. These complexes also are responsible for autoimmune diseases such as Rheumatoid Arthritis and Lupus. In those conditions a large build up of the complexes attack the joints or muscles, respectively thinking these to be foreign invaders. Enzymes eat Circulating Immune Complexes. (2).

In eating away at the substances that cause inflammation, its pain, swelling and redness are reduced. As a consequence pain is relieved. But for athletes the other actions of systemic enzymes are just as important. These enzymes are anti-fibrotic. “Over expression” of Fibrin and Fibrinogen create the matrix in the blood vessels for arteriosclerotic plaque.  Systemic enzymes control this over expression and eat away slowly at established plaque. Systemic Enzymes are also used in Europe to fight thrombosis, blood clots deep in the veins. (3). Isn’t cardiovascular health why most of us started exercising in the first place?

Now science has found that a little critter called a C- reactive protein is the cause of inflammation in blood vessels and can possibly lead to heart disease. Two things destroy C-reactive proteins: aspirin and systemic enzymes. Aspirin use has side effects; the natural enzymes do not.(4).  According to the Wall Street Journal, April 20 1999, 20,000 Americans die from aspirin, ibuprofen and that whole class of Non Steroidal Anti Inflammatory Drugs. That means that more Americans die every year from aspirin and its related drugs than die from AIDS!

The enzymes are also a great blood cleaner. In eating away at Circulating Immune Complexes, necrotic derbies and fibrin in the blood these actions reduce the viscosity of blood by removing the gunk. This is a different mechanism for reducing blood viscosity than aspirin. (5)  To anyone who exercises or plays a sport, thinner blood means improved circulation to working muscles and increased micro circulation. Most folks walk around with blood that’s as thick as catsup! (6). Folks who exercise make that worse by the dehydration they suffer. Many endurance athletes make things worse still by taking the drug EPO which in order to have greater numbers of red blood cells to move oxygen around with. EPO was invented for cancer therapy patients suffering from extreme anemia. It was never meant to augment the hemoglobin count of athletes.  Mainly triathloners, tennis players and cyclists use this drug. They have also been dying of blood clots caused from using this stuff!

Systemic Enzymes help the body to recover faster from exercise, preventing micro trauma from becoming macro trauma. In cases of injury, systemic enzymes are used by pro-athletes to reduce the effects of injury and speed healing. European sport physicians have found that recovery times are cut dramatically. (8).

Now we come to something that over exercisers and endurance athletes are seriously lacking in – an immune system. It is common knowledge in exercise physiology that for each day of heavy training there are two to three days of immune suppression to follow.  If you tag too many workout days together, as we manic compulsive boomers tend to do, then in time the immune system becomes completely trashed. There are numerous cases of marathoners coming down with chronic reoccurring infections because they don’t have anything in their bodies to fight bugs for them. Systemic Enzymes to the rescue!

This is a supplement that I take regularly during periods of heavy training or increased volume, or really any time I have any aches and pains I want to get rid of. I also have many of my clients on them. If it sounds like something you want to try click HERE now and use the coupon code “JASONFE” at checkout for a 15% discount.

13 Responses to Why You Should Take Systemic Enzymes

  1. Weightless Customer October 25, 2011 at 11:22 am #

    I have a minimal amount of arthritis developing in my right knee due to an accident I had not long ago. If these enzymes have ANY chance in helping me or speeding up a recovery of that knee… Then as a faithful customer of yours, I will take your word for it & purchase myself a bottle right now.

    • Hussman September 11, 2012 at 9:35 am #

      I’ve just started taking the Dr. Wong’s brand, but plan to try the one’s Jason got the discount on, and let me tell you they work like a dream. Knee pain reduced within a day, and essentially gone within 3.

  2. heidi October 26, 2011 at 9:47 am #

    I’ve been taking systemic enzymes for years and specifically this brand (which is not Dr. Wong’s brand but he’s sold out often). Good to have you on board! ;)

  3. Phillip Schlueter October 26, 2011 at 11:12 am #

    I know I should be taking this and would benefit greatly from doing so. At age 63 I do recover at an astounding rate, however there is the occasional joint and digestive problem. So not doubt the $145.54 package would be awesome to try. Here’s the thing, if I were to purchase all of the supplements I feel I should be taking for optimum health – I’d be living on the streets. It’s $29.99 for this and $39.99 for that and then the $59.99 and now it’s $99.95 and to make that one better add another $50.00. :( just can’t afford it. Honestly I’m on not one prescription medication but spend an absolute fortune on supplements. Now the decision is which ones do I eliminate to see what Systemic Enzymes can do? I just don’t know!


  4. Daniel October 26, 2011 at 6:18 pm #

    Thanks for the article. I’m a doctor of natural medicine by day and a kettlebell trainer by night. I’ve recommended systemic enzymes to lots of patients and athletes with great results. The research on them is very clear… and has been for years. So much better to encourage healing rather than suppressing inflammation with NSAIDS and other anti-inflammatory meds which the research now indicates decrease pain but also decrease tendon strength, prolong healing and increase risk of future injury.

  5. steve October 26, 2011 at 8:52 pm #

    Jason, just make sure to tell your readers that it is essential to take these enzymes on a empty stomach. 45 minutes before a meal or a 120 minutes after.

  6. AJ October 27, 2011 at 12:09 pm #

    Great Post! Thanks Dr. Wong. Where can I find the sources that you cited? Also, It’d would be great if I could interview you. I am doing research on Rheumatoid Arthritis, and I am at Johns Hopkins University.



  7. Nick October 31, 2011 at 6:52 am #

    Is there a good digestive enzyme anyone can recommend?

  8. Hameed Bhatti October 31, 2011 at 3:24 pm #

    The lInk to the site is broken. Any other onlIne stores you guys can recommend where I can get these from?

  9. jason @ personal trainer November 1, 2011 at 2:25 pm #

    I’ve got a client who has been diagnosed with a minimal amount of arthritis in his wrist, which has been causing him some workout aches and pains.

    Normally I don’t recommend any supplements, but reading this, do you think it would help him? I am tempted.

  10. David W November 1, 2011 at 4:07 pm #

    Can you get these enzymes through any certain foods? Any foods cantain these Enzymes?

    • Juno S September 13, 2012 at 7:57 am #

      I second this question. Are there any ways to get systemic enzymes through foods rather than supplements?

  11. Jason November 2, 2012 at 3:49 pm #

    In my opinion, systemic enzymes should be near the top of one’s “critical” supplement list. One should also really stick with using them; year after year you’ll notice improvements.

    Digestive Enzymes: I use both AST digestive enzymes and digestive enzymes by Dr. Tim Oshea (do a search).

    Systemic Enzymes: I’ve used about four different brands, and currently use AST enzymes (pictured at the top of this post).

    To answer another question: It is very, very difficult to get any systemic action from enzymes found in foods. That’s the whole point: Enzymes when taken with or in foods are consumed through digestion.

    Also, if you’re using enzymes for a medical issue, completely ignore the “suggested” dosage level. Keep slowly increasing your dosage.

    I know one individual that cured his (and about a dozen others’) pancreatic cancer using pancreatic enyzmes and an anti-cancer diet… However, the amount of enzymes required cost about $200.00 a week, and these brave folks would take 30-40 capsules or more daily… we would all benefit from much more open and extensive research on how systemic enzymes can be used.

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